Efficacy of fenugreek seed extract on men's psychological and physical health: a randomized placebo-controlled double-blind clinical trial.
- 2020-05-22
- Journal of complementary & integrative medicine 18(2)
- Heather A Hausenblas
- Kara L Conway
- Kevin R M Coyle
- Emily Barton
- Lacie D Smith
- Michael Esposito
- Charles Harvey
- Dennis Oakes
- David R Hooper
- PubMed: 32441668
- DOI: 10.1515/jcim-2019-0101
Study Design
- Type
- Randomized Controlled Trial (RCT)
- Sample size
- n = 57
- Population
- 57 healthy male volunteers, mean age 26.1 years
- Methods
- Randomized double-blind placebo-controlled trial, parallel design, fenugreek 400 mg/d, fenugreek 500 mg/d, or placebo
- Blinding
- Double-blind
- Duration
- 60 days
- Funding
- Unclear
Objectives
Limited research has examined the effects of fenugreek (Trigonella foenum-graecum L.) supplementation to improve healthy younger men's aging male symptoms. The study objective was to examine whether a fenugreek seed extract would improve healthy men's aging male symptoms, health-related quality of life (HRQoL), grip strength, and anxiety.Methods
Randomized double-blind placebo-controlled trial was employed, using a parallel design, with assessments at baseline, Day 30, and Day 60. Healthy male volunteers (n = 57, mean age = 26.1 years) were randomized to: fenugreek 400 mg/d (n = 19), fenugreek 500 mg/d (n = 19), or placebo group (n = 19).Results
The fenugreek groups reported significant improvements in aging male symptoms, anxiety levels, grip strength, and indicators of HRQoL compared to the placebo group, p's < 0.05. No adverse events were reported.Conclusion
Fenugreek supplementation is an effective nutritional intervention for improving aging male symptoms, anxiety levels, grip strength, and aspects of HRQoL in healthy recreationally active men. Future researchers are encouraged to examine the health and ergogenic effects of fenugreek supplementation in hypogonadal and older populations.Trial registration
Clinicaltrials.gov identifier NCT03528538.Research Insights
The fenugreek groups reported significant improvements in aging male symptoms
- Effect
- Beneficial
- Effect size
- Small
- Dose
- 500 mg/d
The fenugreek groups reported significant improvements in ... grip strength
- Effect
- Beneficial
- Effect size
- Small
- Dose
- 500 mg/d
The fenugreek groups reported significant improvements in ... indicators of HRQoL compared to the placebo group
- Effect
- Beneficial
- Effect size
- Small
- Dose
- 500 mg/d
The fenugreek groups reported significant improvements in ... anxiety levels
- Effect
- Beneficial
- Effect size
- Small
- Dose
- 500 mg/d
Adverse Events Reported
No adverse events were reported.
- Finding
- Reported