Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions.
- 2025-04-08
- NPJ biofilms and microbiomes 11(1)
- Zhuwei Huang
- Jiaye Zhu
- Xiangwen Bu
- Shulai Lu
- Yixian Luo
- Ting Liu
- Ning Duan
- Wenmei Wang
- Yong Wang
- Xiang Wang
- PubMed: 40199865
- DOI: 10.1038/s41522-025-00688-9
Study Design
- Type
- Review
- Methods
- This review aims to comprehensively review the application status of probiotics, prebiotics and engineered probiotics in OPMDs and GPLs, explore their potential mechanisms of action, and anticipate their future clinical use.
Oral potentially malignant disorders (OPMDs) and gastrointestinal precancerous lesions (GPLs) are major public health concerns because of their potential to progress to cancer. Probiotics, prebiotics, and engineered probiotics can positively influence the prevention and management of OPMDs and GPLs. This review aims to comprehensively review the application status of probiotics, prebiotics and engineered probiotics in OPMDs and GPLs, explore their potential mechanisms of action, and anticipate their future clinical use.
Research Insights
Lactobacillus reuteri ATCC PTA 5289 has been associated with reduced levels of oral pathogens in studies of oral health interventions.
- Effect
- Beneficial
- Effect size
- Small