Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

The Effect of Cranberry Consumption on Body Weight and Liver Enzymes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2026-05
  • Food science & nutrition 14(5)
    • Sogand Tavakoli
    • Shadi Ghaemi
    • Mohammad Reza Amini
    • Farhang Djafari
    • Kimia Fathzadeh
    • Mohammadreza Hosseinpour Dogolsar
    • Fatemeh Sheikhhossein
    • Azita Hekmatdoost

Study Design

Type
Review
Population
humans (adults, including those over 50 years, overweight individuals)
Methods
systematic review and meta-analysis; databases searched up to December 2024; inverse variance method
This study aimed to review the literature on studies that evaluated the effects of Cranberry consumption on body weight (BW) and liver enzymes in humans. The following databases were searched up to December 2024: PubMed/Medline, Scopus, ISI Web of Science, Embase, Cochrane Library, and Google Scholar. Data were pooled by the use of the inverse variance method and expressed as weighted mean difference (WMD) with 95% confidence intervals (95% CI). Ten studies were included in this meta-analysis. The results indicated that cranberry consumption significantly reduced body mass index (BMI) (WMD: -0.30 kg/m2, 95% CI: -0.55, -0.04, p = 0.023) while cranberry did not significantly affect aspartate aminotransferase (AST) (WMD: 1.42 IU/L, 95% CI: -0.80, 3.64, p = 0.209), alanine aminotransferase (ALT) (WMD: -0.09 IU/L, 95% CI: -3.63, 3.46, p = 0.962), alkaline phosphatase (ALP) (WMD: -0.54 IU/L, 95% CI: -5.83, 4.75, p = 0.841), waist circumference (WC) (WMD: -0.37 cm, 95% CI: -1.66, 0.91, p = 0.568), and BW (WMD: -0.91 kg, 95% CI: -2.09, 0.27, p = 0.132). Cranberry consumption did lead to a reduction in BMI among adults over 50 years, those classified as overweight, and participants treated for more than 8 weeks. Conversely, cranberry intake was also linked to a significant increase in AST levels within these subgroups. Overall, the findings suggest that cranberry supplementation notably reduced BMI, particularly among older adults, overweight individuals, and participants who engaged in the intervention for more than 8 weeks.

Research Insights

Back to top