The Effect of Moringa oleifera on Body Weight and Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- 2026-05
- Food science & nutrition 14(5)
- Mahnoush Mehrzad Samarin
- Fatemeh Sheikhhossein
- Amir Hossein Khalilkhaneh
- Shadi Ghaemi
- Amin Abbasi
- Hadi Bazyar
- Farhang Djafari
- Zahra Dianati
- Seyed Mojtaba Khodashenas
- Gholamreza Askari
- Mohammad Reza Amini
- PubMed: 42254443
- DOI: 10.1002/fsn3.71899
Study Design
- Type
- Review
- Methods
- A search was conducted through Web of Science, Scopus, and PubMed, along with a manual review of bibliographies, for articles published up to July 2024. Out of 2295 articles, eight randomized controlled trials (RCTs) were included.
Moringa oleifera is suggested as an antihypertensive and anti-obesity agent, but there is insufficient evidence to establish a causal link between Moringa oleifera and reductions in blood pressure and body measurements in humans. This systematic review and meta-analysis seek to examine the effects of Moringa oleifera on body weight and blood pressure. A search was conducted through Web of Science, Scopus, and PubMed, along with a manual review of bibliographies, for articles published up to July 2024. Out of 2295 articles, eight randomized controlled trials (RCTs) were included. The results indicated that Moringa oleifera consumption significantly reduced systolic blood pressure (SBP) by weighted mean differences (WMDs): -6.00 mmHg, p < 0.001 and diastolic blood pressure (DBP) by WMD: -7.32 mmHg, p < 0.001. However, no significant changes were observed in body mass index (BMI) (p = 0.435) and body weight (p = 0.938) compared to those who did not consume Moringa oleifera. Subgroup analyses revealed that SBP significantly decreased in adults consuming 5-10 g/day of Moringa oleifera, particularly in individuals with a BMI below 29.9 and those treated for more than 4 weeks. Furthermore, Moringa oleifera intake was linked to a significant reduction in DBP among participants taking < 10 g/day, those who were overweight, and individuals who supplemented for over 4 weeks. Our systematic review and meta-analysis of RCT indicated that Moringa oleifera had a significant impact on blood pressure, but it did not affect body weight or BMI. Further research is necessary to confirm these findings.
Research Insights
no significant changes were observed in body mass index (BMI) (p = 0.435)
- Effect
- Neutral
- Effect size
- Small
- Dose
- not specified overall
body weight (p = 0.938) compared to those who did not consume Moringa oleifera
- Effect
- Neutral
- Effect size
- Small
- Dose
- not specified overall
diastolic blood pressure (DBP) by WMD: -7.32 mmHg, p < 0.001
- Effect
- Beneficial
- Effect size
- Large
- Dose
- <10 g/day in subgroup that showed effect
Moringa oleifera consumption significantly reduced systolic blood pressure (SBP) by weighted mean differences (WMDs): -6.00 mmHg, p < 0.001
- Effect
- Beneficial
- Effect size
- Moderate
- Dose
- 5-10 g/day in subgroup that showed effect