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The effect of Panax ginseng supplementation on markers of resistance exercise-induced muscle damage: a systematic review.

  • 2024-09
  • The Journal of sports medicine and physical fitness 64(10)
    • Ryland Morgans
    • Jule S Scholten
    • Dave Rhodes
    • Halil I Ceylan
    • Ben Ryan
    • Rafael Oliveira
    • Tom Clifford

Study Design

Type
Systematic Review
Methods
Systematic review of randomized controlled trials following PRISMA guidelines; searched Web of Science, SPORTDiscus, and Medline from December 2021 to February 2022; inclusion criteria: human studies with Panax ginseng and resistance training damaging protocol measuring markers of EIMD; PEDro risk of bias assessment.

Introduction

According to the PRISMA guidelines, this systematic review of randomized controlled trials examined whether Panax ginseng supplementation reduces resistance to exercise-induced muscle damage (EIMD).

Evidence acquisition

Web of Science, SPORTDiscus and Medline databases were searched from the 16th of December 2021 to the 18th of February 2022. Inclusion criteria were studies in humans consuming Panax ginseng that employed resistance training as the damaging muscle protocol and measured markers implicated in the etiology of EIMD (muscle damage, muscle function and muscle soreness). The PEDro risk of bias assessment tool was used to appraise the studies critically.

Evidence synthesis

Conflicting evidence was evident in markers of muscle damage, muscle function and muscle soreness. The quality assessment suggested that all studies had some level of bias.

Conclusions

From 180, six studies were included in the systematic review. The main findings suggest that Panax ginseng does not attenuate markers of EIMD following resistance training. However, research is still preliminary. Adequately powered sample sizes and well-controlled studies are warranted to clarify Panax ginseng's efficacy.

Research Insights

  • Panax Ginseng→Improved Muscle Function

    Conflicting evidence was evident in markers of... muscle function... The main findings suggest that Panax ginseng does not attenuate markers of EIMD following resistance training.

    Effect
    Neutral
    Effect size
    Small
  • Panax Ginseng→Reduced Muscle Damage Marker

    Conflicting evidence was evident in markers of muscle damage... The main findings suggest that Panax ginseng does not attenuate markers of EIMD following resistance training.

    Effect
    Neutral
    Effect size
    Small
  • Panax Ginseng→Reduced Muscle Soreness

    Conflicting evidence was evident in markers of... muscle soreness. The main findings suggest that Panax ginseng does not attenuate markers of EIMD following resistance training.

    Effect
    Neutral
    Effect size
    Small
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