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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Therapeutic Application of Betalains: A Review.

  • 2020-09-17
  • Plants (Basel, Switzerland) 9(9)
    • Elaheh Madadi
    • Sahand Mazloum-Ravasan
    • Jae Sik Yu
    • Ji Won Ha
    • Hamed Hamishehkar
    • Ki Hyun Kim

Study Design

Type
Review
Anthocyanins, betalains, riboflavin, carotenoids, chlorophylls and caramel are the basic natural food colorants used in modern food manufacture. Betalains, which are composed of red-violet betacyanin and yellow betaxanthins, are water-soluble pigments that color flowers and fruits. Betalains are pigments primarily produced by plants of the order Caryophyllales. Because of their anti-inflammatory, cognitive impairment, anticancer and anti-hepatitis properties, betalains are useful as pharmaceutical agents and dietary supplements. Betalains also exhibit antimicrobial and antimalarial effects, and as an example, betalain-rich Amaranthus spinosus displays prominent antimalarial activity. Studies also confirmed the antidiabetic effect of betalains, which reduced glycemia by 40% without causing weight loss or liver impairment. These findings show that betalain colorants may be a promising alternative to the synthetic dyes currently used as food additives.

Research Insights

  • Studies also confirmed the antidiabetic effect of betalains, which reduced glycemia by 40% without causing weight loss or liver impairment.

    Effect
    Beneficial
    Effect size
    Moderate
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