Vitamin B12 and Increased Hemoglobin Levels

Doses used in studies

µg/day: 1,000 (median 1,000, IQR 1,000–1,000) — 1 study

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 1 study

1 of 1 paper

Comparison of Efficacy and Safety of Parenteral vs Oral Route of Vitamin B12 Supplementation for the Treatment of Vitamin B12 Deficiency Anemia in Children: A Systematic Review.

2025-02-18
Systematic Review
Nutrition reviews 83(9)
- Meenakshi Sachdeva
- Abhishek Purohit
- Meenakshi Malik
- Lovely Jain
- Pranita Pradhan
- Joseph L Mathew

PubMed: 39964959
DOI: 10.1093/nutrit/nuae227

2 Insights on

Increased Hemoglobin Levels

High evidence
Clinical

The changes from baseline in ... hemoglobin (2.7 [0.4, 4.6] vs 0.5 [-0.1, 1.2] g/dL, P = .001) were also significantly greater with the parenteral route.

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 1000 µg initially parenterally followed by parenteral or oral therapy (dose not specified for maintenance)