Best Supplements for Increased Hemoglobin Levels
Ranked by research evidence. Compare 34 supplements across 52 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- 1IronHigh evidence6 studies
Across 6 studies, 5 reported beneficial small-sized effects of iron on increasing hemoglobin levels. The median study duration was approximately 8 weeks (58 days across 2 studies). Most evidence comes from iron-deficient or at-risk populations, including blood donors, non-anaemic iron-deficient women, and patients with celiac disease.
- Moderate evidence5 studies
Across 5 studies, 4 reported beneficial effects of vitamin D on hemoglobin levels, with effect sizes ranging from small to moderate. The predominant effect size was moderate, and effects were typically observed at a median study duration of 273 days (about 9 months). The most-studied populations were clinical groups, including children with inflammatory bowel disease, adults with tuberculosis, and patients with celiac disease, with no clear dose range converging across studies.
Product matchViva Naturals — Vitamin D3 with Organic Liquid Coconut Oil125 mcg · $15.16 · ★5.0 (208) - Low evidence3 studies
Across 3 studies (2 with completed results), 2 reported beneficial small-sized effects on hemoglobin levels in children with iron deficiency anemia. One study was a protocol with no results (neutral). Effects were observed at 4–16 weeks. Doses were not consistently reported across studies.
- HighIronAcross 6 studies, 5 reported beneficial small-sized effects of iron on increasing hemoglobin levels. The median study duration was approximately 8 weeks (58 days across 2 studies). Most evidence comes from iron-deficient or at-risk populations, including blood donors, non-anaemic iron-deficient women, and patients with celiac disease.5 beneficial1 neutral6 studies
- ModerateVitamin DAcross 5 studies, 4 reported beneficial effects of vitamin D on hemoglobin levels, with effect sizes ranging from small to moderate. The predominant effect size was moderate, and effects were typically observed at a median study duration of 273 days (about 9 months). The most-studied populations were clinical groups, including children with inflammatory bowel disease, adults with tuberculosis, and patients with celiac disease, with no clear dose range converging across studies.4 beneficial1 neutral5 studies
- LowLactoferrinAcross 3 studies (2 with completed results), 2 reported beneficial small-sized effects on hemoglobin levels in children with iron deficiency anemia. One study was a protocol with no results (neutral). Effects were observed at 4–16 weeks. Doses were not consistently reported across studies.2 beneficial1 neutral3 studies
- LowZincAcross 3 meta-analyses, 2 reported beneficial moderate-sized effects on hemoglobin levels in people with sickle cell disease and celiac disease, while 1 found no clear effect in people living with HIV on HAART. The evidence base is small, and doses were not consistently reported.2 beneficial1 neutral3 studies