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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Cordyceps

Safety profile

3 studies reporting safety data

Across 3 clinical studies, no specific adverse events were found to be significantly increased with Cordyceps compared to control. Two studies reported no significant difference in the rates of gastrointestinal adverse reactions (RR 0.80, 95%CI 0.47–1.37) and liver/renal damage (RR 0.32, 95%CI 0.09–1.10). Two additional studies described Cordyceps as generally well tolerated, with one meta-analysis noting a higher rate of adverse drug reactions in the control group than in the Cordyceps group.

Caveats: Limited evidence base; absence of reported adverse events does not establish safety. Findings reflect specific strains and formulations used in the included studies; other preparations may differ.

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