Vitamin B2 and Reduced Blood Pressure

• Can riboflavin offer a novel personalised strategy for maintaining healthy blood pressure in pregnancy in populations globally?

  • 2025-09-08
  • Review
  • BMJ nutrition, prevention & health 8(2)
  • • Bethany Duffy
    • Anmol Patted
    • Rupsa C Boelig
    • Mary Murphy
    • Kristina Pentieva
    • Mary Ward
    • Diane Lees-Murdock
    • Victor Garcia
    • Frank Barry
    • Vanessa Short
    • Catherine Hughes
    • Richard Derman
    • Helene McNulty

  • PubMed: 41768514
  • DOI: 10.1136/bmjnph-2025-001212

  1 Insight on

  • Reduced Blood Pressure

  • Low evidence

  randomised trials show that supplemental riboflavin can effectively lower blood pressure specifically in individuals with the variant MTHFR 677TT genotype, independently of antihypertensive medications.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes