Vitamin B3 and Increased Adiponectin Levels

• The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials.

  • 2023-10-03
  • Systematic Review · n = 144
  • Frontiers in nutrition 10
  • • You Baichuan
    • Marcela Gomes Reis
    • Sogand Tavakoli
    • Navideh Khodadadi
    • Mohammad Hassan Sohouli
    • Nathalia Sernizon Guimarães

  • PubMed: 37854354
  • DOI: 10.3389/fnut.2023.1208734

  4 Insights on

  • Increased Adiponectin Levels

  • High evidence

  increasing adiponectin (WMD: 1.59 μg/mL, 95% CI: 0.49 to 2.68, p = 0.004) in humans compared with control groups.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• The effect of niacin on inflammatory markers and adipokines: a systematic review and meta-analysis of interventional studies.

  • 2024-05-18
  • Meta-Analysis
  • European journal of nutrition 63(6)
  • • Esmaeil Yousefi Rad
    • Somayeh Saboori
    • Jonathan Tammam
    • Pariyarath Sangeetha Thondre
    • Shelly Coe

  • PubMed: 38761279
  • DOI: 10.1007/s00394-024-03425-8

  4 Insights on

  • Increased Adiponectin Levels

  • High evidence
  • Rigorous Journal

  Niacin administration also substantially elevated Adiponectin (SMD: 3.52, 95% CI: 0.95 to 6.1, p = 0.007).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  ≤ 1000 mg/day