The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials.
- 2023-10-03
- Systematic Review · n = 144
- Frontiers in nutrition 10
- You Baichuan
- Marcela Gomes Reis
- Sogand Tavakoli
- Navideh Khodadadi
- Mohammad Hassan Sohouli
- Nathalia Sernizon Guimarães
- PubMed: 37854354
- DOI: 10.3389/fnut.2023.1208734
- High evidence
The pooled findings showed that NAD+ precursor supplementation has an effect on lowering BMI (weighted mean difference (WMD): -0.19 kg/m2, 95% confidence interval (CI): -0.29 to -0.09, p < 0.001)...subgroup analysis showed that BMI reduction was greater when receiving nicotinic acid (NA) supplementation than nicotinamide (NE) supplementation.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes