Correlation of changes in HIF-1α and p53 expressions with vitamin B3 deficiency in skin cancer patients.
- 2019-10
- RCT
- Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 154(5)
- Ting Liu
- Hao Yang
- Yunzhu Mou
- Hao Zhang
- PubMed: 29064206
- DOI: 10.23736/s0392-0488.17.05775-3
- High evidence
- Clinical
The protein and mRNA expression levels of HIF-1α and p53 in tissues of skin cancer patients were significantly decreased at 1 week after the oral administration of vitamin B3 compared with those before the oral administration of vitamin B3 (P<0.05)
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 500 mg/day