Vitamin B6 and Reduced Nausea and Vomiting Severity

• The effects of pyridoxine (vitamin B6) supplementation in nausea and vomiting during pregnancy: a systematic review and meta-analysis.

  • 2023-01-31
  • Meta-Analysis
  • Archives of gynecology and obstetrics 308(4)
  • • Ranil Jayawardena
    • Shahana Majeed
    • Piumika Sooriyaarachchi
    • Udara Abeywarne
    • Probhodana Ranaweera

  • PubMed: 36719452
  • DOI: 10.1007/s00404-023-06925-w

  1 Insight on

  • Reduced Nausea and Vomiting Severity

  • High evidence
  • Pregnant Women

  Supplementation of pyridoxine alone as well as combined treatment of pyridoxine with an active ingredient as the intervention significantly improved the symptoms of nausea according to Rhode's score [0.78 [95% CI: 0.26, 1.31; p=0.003; I2=57%, p=0.10)] and PUQE score [0.75 (95% CI: 0.28, 1.22; p=0.002; I2=0%, p=0.51)], respectively.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes