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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin B6 and Reduced Pain

Doses used in studies

mg/day: 80–1,200 (median 640, IQR 360–920) — 2 studies

Time to effect

Median: 8.6 weeks · IQR 8.6 weeks–8.6 weeks · Range 8.6 weeks–8.6 weeks — Reported in 1 of 2 studies

2 of 2 papers

Effect of vitamin B6 on pain, disease severity, and psychological profile of fibromyalgia patients; a randomized, double-blinded clinical trial.
- 2022-07-13
- RCT · n = 90
- BMC musculoskeletal disorders 23(1)
- - Banafsheh Ghavidel-Parsa
  - Arvin Naeimi
  - Faeze Gharibpoor
  - Nazila Sattari
  - Atefeh Jafari
  - Irandokht Shenavar Masooleh
  - Ali Montazeri
- PubMed: 35831850
- DOI: 10.1186/s12891-022-05637-7
3 Insights on
- Reduced Pain
- High evidence
- Clinical
there was no statistically significant intergroup difference regarding primary outcomes
Effect
Neutral
Effect size
Small
Significant
No
Dose
80 mg daily
Clinical usefulness of nutraceutics with acetyl-L-carnitine, α-lipoic acid, phosphatidylserine, curcumin, C, E and B-group vitamins in patients awaiting for carpal tunnel release during COVID-19 pandemic: a randomized controlled open label prospective study.
- 2023-06-23
- RCT
- Acta bio-medica : Atenei Parmensis 94(S2)
- - Marco D'Orio
  - Rocco De Vitis
  - Giuseppe Taccardo
  - Lorenzo Rocchi
  - Federico Ferrari
  - Andrea Perna
  - Marco Passiatore
- PubMed: 37366197
- DOI: 10.23750/abm.v94is2.12513
5 Insights on
- Reduced Pain
- High evidence
- Clinical
as well as BCTQ symptoms subscale, and the pain.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
600 mg twice daily