Vitamin B9 and Reduced Fatigue

• The potential adding therapeutic effect of pentoxifylline and/or folic acid for chronic kidney disease patients: randomized controlled trial.

  • 2025-08-18
  • RCT · n = 80
  • BMC nephrology 26(1)
  • • Amira Reda Muhammad Galal
    • Nahla Mohamed Teama
    • Karema Abu-Elfotuha
    • Ahmed D Alatawi
    • Hanan Alshareef
    • Ahmed M E Hamdan
    • Ahmed Aljabri
    • Mohannad Alshibani
    • Zeinab AlKasaby Mahmoud Zalat

  • PubMed: 40826392
  • DOI: 10.1186/s12882-025-04399-3

  2 Insights on

  • Reduced Fatigue

  • High evidence
  • Clinical

  There was a significant improvement in renal function biochemical parameters and a significant reduction in the FAS for the intervention groups compared to the control group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  therapeutic dose