Vitamin B9 and Reduced Neural Tube Defect Prevalence

• Comparing Folic Acid Interventions and Arsenic Reduction Strategies for Neural Tube Defect Prevention in Bangladesh: A Systematic Review and Decision Analysis.

  • 2025-06
  • Meta-Analysis
  • Birth defects research 117(6)
  • • Chih-Fu Wei
    • Ernani F Choma
    • Xingyan Wang
    • Carrie G Wade
    • Ya Luan Hsiao
    • Diane Bao
    • Sudipta K Mukherjee
    • David C Christiani
    • Marc G Weisskopf
    • Liming Liang
    • Maitreyi Mazumdar

  • PubMed: 40552686
  • DOI: 10.1002/bdr2.2494

  1 Insight on

  • Reduced Neural Tube Defect Prevalence

  • High evidence
  • Pregnant Women

  Folic acid fortification reduced the prevalence of NTDs to 11.1 and 9.1 per 10,000 births among high exposure and low exposure groups, respectively.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes