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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin C and Improved Insulin Sensitivity

Doses used in studies

mg/day: 80 (median 80, IQR 80–80) — 1 study

Time to effect

Median: 8 days · IQR 8 days–8 days · Range 8 days–8 days — Reported in 1 of 1 study

1 of 1 paper

Metabolic and Neuroenergetic Effects of Intranasal Vitamin C Application in the Human Brain.
- 2025-12-11
- RCT
- Nutrients 17(24)
- - Lena-Christin Ingwersen
  - Alina Kistenmacher
  - Uwe H Melchert
  - Kerstin M Oltmanns
- PubMed: 41470820
- DOI: 10.3390/nu17243875
1 Insight on
- Improved Insulin Sensitivity
- High evidence
- Rigorous Journal
- Adults
In the obese group, vitamin C application acutely suppressed the physiological insulin response on the first experimental day (p = 0.003).
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
80 mg ascorbic acid/day