Cholecalciferol (vitamin D3): efficacy, safety, and implications in public health.
- 2025-06-09
- Review
- Frontiers in nutrition 12
- Esteban Ortiz-Prado
- Jorge Vasconez-Gonzalez
- Juan S Izquierdo-Condoy
- Isaac A Suárez-Sangucho
- José Guillermo Prieto-Marín
- Karen Bereniss Villarreal-Burbano
- Mateo Alejandro Barriga-Collantes
- John Alexander Altamirano-Castillo
- Domenic Anahi Borja-Mendoza
- Jean Carlo Pazmiño-Almeida
- María Paz Cadena-Padilla
- PubMed: 40551736
- DOI: 10.3389/fnut.2025.1579957
- Low evidence
High-dose vitamin D₃ has demonstrated benefits in specific populations, including improved bone mineral density, immune homeostasis, glycemic control, and reduced inflammation.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes