Vitamin D and Increased HDL Cholesterol Levels

• Can vitamin D supplementation affect cardiometabolic factors in children and adolescence with overweight and obesity? A grade-assessed systematic review and meta-analysis of randomized controlled trials.

  • 2025-11-25
  • Meta-Analysis · n = 440
  • BMC pediatrics 25(1)
  • • Amir Hossein Faghfouri
    • Mahsa Mahmoudinezhad
    • Pedram Pam
    • Sanaz Barazandeh
    • Fatemeh Faramarzi
    • Yousef Mohammadpour
    • Vali Musazadeh
    • Shahsanam Gheibi

  • PubMed: 41291584
  • DOI: 10.1186/s12887-025-05795-2

  9 Insights on

  • Increased HDL Cholesterol Levels

  • High evidence
  • Children

  it was accompanied with a significant reduction in HDL-C level

  Effect

  Harmful

  Effect size

  Small

  Significant

  Yes

• The effect of vitamin D2 on lipid profile, anthropometric indices, blood pressure, and inflammatory and glycemic biomarkers in humans: A systematic review and meta-analysis of randomized controlled trials.

  • 2024-10
  • Meta-Analysis
  • Prostaglandins & other lipid mediators 174
  • • Zhihong Zhou
    • Jiyuan Liu
    • Hui Zhang
    • Kousalya Prabahar
    • Benjamin Hernández-Wolters
    • Yuanhong Yuan

  • PubMed: 39154789
  • DOI: 10.1016/j.prostaglandins.2024.106883

  12 Insights on

  • Increased HDL Cholesterol Levels

  • High evidence

  No statistically significant association was observed between vitamin D2 administration and ... HDL-C

  Effect

  Neutral

  Effect size

  Small

  Significant

  No