Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Vitamin D and Increased HDL Cholesterol Levels

Research synthesisVery low evidenceSmall effect3 studies · 1 beneficial · 1 neutral · 1 harmful

Across 3 studies, 1 reported a small beneficial effect of vitamin D on increasing HDL cholesterol levels in pediatric patients with MASLD, 1 reported a small harmful effect (reducing HDL-C) in obese/overweight children and adolescents, and 1 reported no significant association. The evidence is conflicting, and the predominant effect size is small but inconsistent. No consistent dose or form emerged across studies.

  • Studied populations: pediatric patients with MASLD; obese/overweight children and adolescents

Caveats: Evidence base is small (only 3 studies) and findings are contradictory—one study shows a beneficial effect while another shows a harmful effect on HDL-C. Many of the included studies did not reach statistical significance, with only 2 of 3 reporting significant results. Conclusions should be considered preliminary, and the effect may depend on specific population characteristics.

Generated Jul 14, 2026
3 of 3 papers
Back to top