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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Vitamin D and Reduced Body Weight

Research synthesisVery low evidenceSmall effect3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, 1 reported a moderate beneficial effect on reduced body weight, while 2 found neutral small effects. The one beneficial finding was from a review of a combination treatment (Salacia + vitamin D), not vitamin D alone. The median study duration was 112 days (16 weeks) in the one study that reported duration. Evidence is limited and does not support a consistent independent effect of vitamin D on weight loss.

  • Studied populations: hypertensive obese obstructive sleep apnea patients (one study)

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Only 1 of 3 studies reported a statistically significant finding, and that was for a combination intervention (Salacia + vitamin D), making it unclear whether vitamin D alone is responsible. The two neutral studies suggest no effect on weight, and the beneficial study is a low-evidence review from 2015.

Generated Jun 12, 2026
Doses used in studies
  • IU/day: 5,000 (median 5,000, IQR 5,000–5,000) — 1 study
Time to effect
Median: 3.7 months · IQR 3.7 months–3.7 months · Range 3.7 months–3.7 months — Reported in 1 of 3 studies
3 of 3 papers
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