Vitamin D and Reduced Fall Incidence

Doses used in studies

Safety in these studies

all-cause mortalityNo significant differenceSerious adverse eventrisk ratio (95% CI) of 0.95 (0.87-1.04)
This regimen showed no increase in all-cause mortality, with a risk ratio (95% CI) of 0.95 (0.87-1.04).
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations
fallsNo significant differencerisk ratios of 1.02 (0.98-1.05)
it did not significantly reduce the risks of falls and fractures, with risk ratios of 1.02 (0.98-1.05) and 0.95 (0.87-1.04) respectively.
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations
fracturesNo significant differenceSerious adverse eventrisk ratios ... 0.95 (0.87-1.04)
it did not significantly reduce the risks of falls and fractures, with risk ratios of 1.02 (0.98-1.05) and 0.95 (0.87-1.04) respectively.
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations
fallsReported
further research is needed to determine if this method would increase the incidence of falls. Therefore, it is not recommended at this stage due to the lack of demonstrated safety in additional relevant RCTs.
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations

1 of 1 paper

Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations and the incidence rates of fractures, falls, and mortality in elderly individuals: A systematic review and meta-analysis.