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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Vitamin D and Reduced Inflammation

Research synthesisLow evidenceSmall effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported small beneficial effects of vitamin D on reducing inflammation. 3 of 4 studies reported statistically significant findings. The evidence is drawn from clinical populations including rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis, as well as general adult groups. Doses, forms, and study durations were not consistently reported across the included studies.

  • Studied populations: patients with rheumatoid arthritis, axial spondyloarthritis, and psoriatic arthritis

Caveats: Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Most studies lacked dose and form details, limiting practical applicability.

Generated May 22, 2026
4 of 4 papers
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