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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Vitamin D and Reduced Insulin Levels

Research synthesisModerate evidenceMixed effect size3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 meta-analyses, 2 reported beneficial moderate-to-large effects of vitamin D supplementation on reducing insulin levels in patients with diabetes/prediabetes and women with PCOS, while one large meta-analysis in overweight/obese children found no significant effect. The predominant effect size among beneficial studies was mixed (moderate to large). No dose or form data were consistently reported across studies.

  • Studied populations: patients with diabetes or prediabetes, women with polycystic ovary syndrome (PCOS)

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. One high-quality meta-analysis in overweight/obese children and adolescents found no significant effect, suggesting benefit may be population-dependent. No dose or form information was extracted, limiting practical application.

Generated Jun 15, 2026
3 of 3 papers
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