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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin D and Reduced Total Cholesterol Levels

Doses used in studies

IU/day: 1,000 (median 1,000, IQR 1,000–1,000) — 1 study

Time to effect

Median: 6 weeks · IQR 6 weeks–6 weeks · Range 6 weeks–6 weeks — Reported in 1 of 2 studies

2 of 2 papers

The effects of vitamin D supplementation on serum lipid profiles in people with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials.
- 2024-06-05
- Systematic Review · n = 1,711
- Frontiers in nutrition 11
- - Qingyang Lu
  - Qingyue Liang
  - Yue Xi
- PubMed: 38903615
- DOI: 10.3389/fnut.2024.1419747
4 Insights on
- Reduced Total Cholesterol Levels
- High evidence
- Clinical
However, vitamin D supplementation failed to improve low-density lipoprotein (LDL) levels and total cholesterol (TC) levels.
Effect
Neutral
Effect size
Small
Significant
No
Dose
not specified individually per trial
Vitamin D and Evening Primrose Oil Administration Improve Glycemia and Lipid Profiles in Women with Gestational Diabetes.
- 2016-01-19
- RCT · n = 60
- Lipids 51(3)
- - Mehri Jamilian
  - Maryam Karamali
  - Mohsen Taghizadeh
  - Nasrin Sharifi
  - Zahra Jafari
  - Mohammad Reza Memarzadeh
  - Mahnaz Mahlouji
  - Zatolla Asemi
- PubMed: 26781763
- DOI: 10.1007/s11745-016-4123-3
9 Insights on
- Reduced Total Cholesterol Levels
- High evidence
- Clinical
TC/HDL (-0.3 ± 0.4 vs. +0.3 ± 0.5 mg/dL, P < 0.001)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
1000 IU/day