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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Vitamin D and Reduced Triglyceride Levels

Research synthesisModerate evidenceSmall effect7 studies · 4 beneficial · 3 neutral · 0 harmful

Across 7 studies, 4 reported beneficial small-sized effects of vitamin D supplementation on reducing triglyceride levels, while 3 found neutral effects. The evidence is strongest in clinical populations such as type 2 diabetes, gestational diabetes, and metabolic-associated fatty liver disease. Median study duration was 42 days, but this is based on only 1 study.

  • Studied populations: clinical populations (type 2 diabetes, gestational diabetes, metabolic-associated fatty liver disease, polycystic ovary syndrome) and overweight/obese children

Caveats: While the majority of studies show a beneficial effect, nearly half (3 of 7) reported no significant improvement, suggesting the effect may be modest and context-dependent. Most trials involved clinical populations with metabolic conditions, so benefits may not generalize to healthy individuals. Duration data are limited (only 1 study reported a specific intervention period).

Generated Jun 14, 2026
Doses used in studies
  • IU/day: 1,000 (median 1,000, IQR 1,0001,000) 1 study
Time to effect
Median: 6 weeks · IQR 6 weeks6 weeks · Range 6 weeks6 weeks — Reported in 1 of 7 studies
7 of 7 papers
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