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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin D3 and Reduced C-terminal Telopeptide Level

Doses used in studies

IU/day: 2,000 (median 2,000, IQR 2,000–2,000) — 1 study

Time to effect

Median: 36.5 months · IQR 36.5 months–36.5 months · Range 36.5 months–36.5 months — Reported in 1 of 1 study

1 of 1 paper

Effect of Vitamin D3, Omega-3 Fatty Acids, and Exercise on Serum Sclerostin Levels and Bone Turnover Markers.
- 2024-12-09
- RCT · n = 1,848
- The Journal of clinical endocrinology and metabolism 110(9)
- - Elena Tsourdi
  - Stephanie Gängler
  - Melanie Kistler-Fischbacher
  - Martina Rauner
  - Bess Dawson-Hughes
  - E John Orav
  - Li-Tang Tsai
  - Wei Lang
  - John A Kanis
  - Robert Theiler
  - Andreas Egli
  - Heike A Bischoff-Ferrari
  - Lorenz C Hofbauer
- PubMed: 39657964
- DOI: 10.1210/clinem/dgae859
3 Insights on
- Reduced C-terminal Telopeptide Level
- High evidence
- Large Human Trial
- Elderly
For P1NP and β-CTx there were no significant effects for any of the individual treatments and treatment combinations.
Effect
Neutral
Effect size
Small
Significant
No
Dose
2000 IU/day