Vitamin E and Reduced Alanine Aminotransferase Level

• Efficacy and Safety of Vitamin E in Adults With Metabolic Dysfunction-Associated Steatohepatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2025-07-29
  • Review
  • Cureus 17(7)
  • • Helai Hussaini
    • Manpreet Kaur Dhanjal
    • Rahman Hameed Mohammed Abdul
    • Olaniyi Fadeyi
    • Najeeha A Bhatti
    • Mohammed Qasim Rauf
    • Calvin R Wei
    • Adil Amin

  • PubMed: 40895855
  • DOI: 10.7759/cureus.88949

  4 Insights on

  • Reduced Alanine Aminotransferase Level

  • Low evidence
  • Clinical

  vitamin E significantly reduced serum alanine aminotransferase levels compared to placebo (mean difference (MD): -12.27, 95% confidence interval (CI): -16.66 to -7.89)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  300 to 800 mg daily