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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Alanine Aminotransferase Level

Ranked by research evidence. Compare 17 supplements across 22 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence3 studies

    Across 3 studies, all reported beneficial effects of vitamin E on reducing alanine aminotransferase (ALT) levels, with effect sizes ranging from small to moderate. Two of three studies found statistically significant reductions. The evidence primarily comes from clinical populations with non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatohepatitis (MASH), with a median study duration of 72 days (approximately 10 weeks). The most-studied dose range is 298–1000 IU/day.

    Dose: 298–1000 IU/day
    Product match
    Bluebonnet NutritionVitamin E
    400 IU · $28.76 · ★5.0 (136)
17 supplements
  • LowVitamin EAcross 3 studies, all reported beneficial effects of vitamin E on reducing alanine aminotransferase (ALT) levels, with effect sizes ranging from small to moderate. Two of three studies found statistically significant reductions. The evidence primarily comes from clinical populations with non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated steatohepatitis (MASH), with a median study duration of 72 days (approximately 10 weeks). The most-studied dose range is 298–1000 IU/day. · Dose: 298–1000 IU/day3 beneficial3 studies
  • Thistle2 beneficial2 studies
  • Red Grape2 beneficial2 studies
  • Black Cumin1 beneficial1 neutral2 studies
  • Artichoke1 beneficial1 study
  • L-Carnitine1 beneficial1 study
  • Artichoke1 beneficial1 study
  • Lactobacillus helveticus R00521 beneficial1 study
  • Lactobacillus rhamnosus LRa051 beneficial1 study
  • Vitamin D1 beneficial1 study
  • Vitamin C1 beneficial1 study
  • Reishi1 neutral1 study
  • Mulberry1 neutral1 study
  • Taurine1 neutral1 study
  • raspberry1 neutral1 study
  • Coffee1 neutral1 study
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