Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Vitamin E and Reduced Oxidative Stress

Doses used in studies

mg/day: 335 (median 335, IQR 335–335) — 1 study

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Effects of vitamins C and E supplementation combined with 12-week resistance training in older women with sarcopenia: A randomized, double-blind, placebo-controlled trial.
- 2025-08-22
- RCT
- Medicine 104(34)
- - Xu Liu
  - Bo Chen
  - Yutian Jin
  - Feiyan Zhong
  - Yunjuan Zhang
  - Yu Li
  - Yun Zhang
  - Runhong Cui
  - Bing Wu
  - Cui Li
  - Sheng Xu
  - Xiaohong Chen
- PubMed: 40859523
- DOI: 10.1097/md.0000000000043976
15 Insights on
- Reduced Oxidative Stress
- High evidence
- Clinical
the AS group had increased GSH (P < .001, d = 1.52) and GSH/GSSG ratio (P < .001, d = 1.52), and reduced GSSG (P < .001, d = 0.96) and malondialdehyde (P < .001, d = 1.65) compared to the PLA group
Effect
Beneficial
Effect size
Large
Significant
Yes
Dose
335 mg/d
The Effects of Antioxidant Supplementation on Soccer Performance and Recovery: A Critical Review of the Available Evidence.
- 2024-11-06
- Review
- Nutrients 16(22)
- - Athanasios Poulios
  - Konstantinos Papanikolaou
  - Dimitrios Draganidis
  - Panagiotis Tsimeas
  - Athanasios Chatzinikolaou
  - Athanasios Tsiokanos
  - Athanasios Z Jamurtas
  - Ioannis G Fatouros
- PubMed: 39599590
- DOI: 10.3390/nu16223803
7 Insights on
- Reduced Oxidative Stress
- Moderate evidence
- Rigorous Journal
reduce oxidative stress (malondialdehyde, glutathione, total antioxidant capacity, superoxide dismutases, protein carbonyls, ascorbate, glutathione peroxidase, and paraoxonase 1)
Effect
Beneficial
Effect size
Small
Significant
Yes