Association of Dietary Vitamin K1 Intake With the Incidence of Cataract Surgery in an Adult Mediterranean Population: A Secondary Analysis of a Randomized Clinical Trial.
- 2017-06-01
- RCT · n = 5,860
- JAMA ophthalmology 135(6)
- María L Camacho-Barcia
- Mònica Bulló
- Jesús F Garcia-Gavilán
- Miguel Ruiz-Canela
- Dolores Corella
- Ramón Estruch
- Montserrat Fitó
- Alfredo García-Layana
- Fernando Arós
- Miquel Fiol
- José Lapetra
- Lluis Serra-Majem
- Xavier Pintó
- Ana García-Arellano
- Ernest Vinyoles
- José Vicente Sorli
- Jordi Salas-Salvadó
- PubMed: 28494067
- DOI: 10.1001/jamaophthalmol.2017.1076
- High evidence
- Large Human Trial
- Elderly
Participants in the highest tertile of dietary vitamin K1 intake had a lower risk of cataracts than those in the lowest tertile (hazard ratio, 0.71; 95% CI, 0.58-0.88; P = .002), after adjusting for potential confounders.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes