Vitamin K1 and Reduced Fracture Risk

• Vitamin K intake and the risk of fractures: A meta-analysis.

  • 2017-04
  • Meta-Analysis · n = 1,114
  • Medicine 96(17)
  • • Guangliang Hao
    • Bei Zhang
    • Mingyong Gu
    • Chen Chen
    • Qiang Zhang
    • Guichun Zhang
    • Xuecheng Cao

  • PubMed: 28445289
  • DOI: 10.1097/md.0000000000006725

  1 Insight on

  • Reduced Fracture Risk

  • High evidence
  • Clinical

  Dose-response analysis indicated that the pooled RR of fracture for an increase of 50 μg dietary vitamin K intake per day was 0.97 (95% CI: 0.95-0.99) without heterogeneity among studies (I = 25.9%, P for heterogeneity = .25).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  50 μg/day increment