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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Fracture Risk

Ranked by research evidence. Compare 16 supplements across 21 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence5 studies

    Across 5 studies, 3 reported beneficial effects (small to moderate) on fracture risk, while 2 found neutral effects. The predominant effect size among beneficial studies was small. Evidence is strongest for menopausal and postmenopausal women, with some data supporting vitamin D-fortified foods. Studies using high-dose bolus administration showed neutral results, and the most recent large-scale trials have failed to replicate earlier benefits, suggesting effect may be limited to certain populations or formulations.

    Product match
    Viva NaturalsVitamin D3 with Organic Liquid Coconut Oil
    125 mcg · $15.16 · ★5.0 (208)
16 supplements
  • LowVitamin DAcross 5 studies, 3 reported beneficial effects (small to moderate) on fracture risk, while 2 found neutral effects. The predominant effect size among beneficial studies was small. Evidence is strongest for menopausal and postmenopausal women, with some data supporting vitamin D-fortified foods. Studies using high-dose bolus administration showed neutral results, and the most recent large-scale trials have failed to replicate earlier benefits, suggesting effect may be limited to certain populations or formulations.3 beneficial2 neutral5 studies
  • Vitamin K1 beneficial1 neutral2 studies
  • Shatavari1 beneficial1 study
  • Red Clover1 beneficial1 study
  • Prickly Pear1 beneficial1 study
  • Black Cohosh1 beneficial1 study
  • Olive1 beneficial1 study
  • Cornus1 beneficial1 study
  • Tea1 beneficial1 study
  • Pine1 beneficial1 study
  • Onion1 beneficial1 study
  • Calcium1 beneficial1 study
  • Vitamin K11 beneficial1 study
  • Eleuthero1 beneficial1 study
  • Cissus quadrangularis1 beneficial1 study
  • Black Cumin1 beneficial1 study
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