Vitamin K2 and Increased Total Hip Bone Mineral Density

• Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.

  • 2022-06-16
  • Meta-Analysis · n = 6,853
  • Journal of bone and mineral metabolism 40(5)
  • • Ming Zhou
    • Shiliang Han
    • Wenpeng Zhang
    • Dan Wu

  • PubMed: 35711002
  • DOI: 10.1007/s00774-022-01342-6

  2 Insights on

  • Increased Total Hip Bone Mineral Density

  • High evidence
  • Clinical

  Vitamin K2 was associated with a significantly increased percentage change of lumbar BMD and forearm BMD (WMD 2.17, 95% CI [1.59-2.76] and WMD 1.57, 95% CI [1.15-1.99]).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes