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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Astaxanthin and Reduced Oxidative Stress

Doses used in studies

mg/day: 8 (median 8, IQR 8–8) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Redox-sensitive miRNAs and Humanin could mediate effects of exercise and astaxanthin on oxidative stress and inflammation in type 2 diabetes.
- 2025-11-17
- RCT · n = 15
- Scientific reports 15(1)
- - Aref Basereh
  - Karen Khoramipour
  - Najmeh Hosseini
  - Mahdieh HajHosseini
  - Adeleh Khodabakhshi
  - Ladan Amirkhosravi
  - Kayvan Khoramipour
- PubMed: 41249265
- DOI: 10.1038/s41598-025-23914-y
11 Insights on
- Reduced Oxidative Stress
- High evidence
- Rigorous Journal
- Clinical
Both CT and AST enhanced antioxidant defenses and reduced IF, with CT + S showing the best effects.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
8 mg/day
The Effects of Antioxidant Supplementation on Soccer Performance and Recovery: A Critical Review of the Available Evidence.
- 2024-11-06
- Review
- Nutrients 16(22)
- - Athanasios Poulios
  - Konstantinos Papanikolaou
  - Dimitrios Draganidis
  - Panagiotis Tsimeas
  - Athanasios Chatzinikolaou
  - Athanasios Tsiokanos
  - Athanasios Z Jamurtas
  - Ioannis G Fatouros
- PubMed: 39599590
- DOI: 10.3390/nu16223803
7 Insights on
- Reduced Oxidative Stress
- Moderate evidence
- Rigorous Journal
reduce oxidative stress (malondialdehyde, glutathione, total antioxidant capacity, superoxide dismutases, protein carbonyls, ascorbate, glutathione peroxidase, and paraoxonase 1)
Effect
Beneficial
Effect size
Small
Significant
Yes