avocado and Reduced Triglyceride Levels

Research synthesisLow evidenceSmall effect4 studies · 1 beneficial · 3 neutral · 0 harmful

Across 4 studies, only 1 reported a moderate beneficial effect on triglycerides, while 3 found neutral effects. The beneficial study used 1 avocado per day (∼180 g) for 21 days in adults with elevated triglycerides, showing a 17.4% reduction. However, the evidence is predominantly neutral and inconsistent, with most studies showing small non-significant effects.

Studied populations: Adults with elevated triglycerides (135-499 mg/dL)

Caveats: Only one of four studies reached statistical significance; the majority found no significant effect on triglycerides. The beneficial study was short-term (21 days) and involved a controlled feeding design. Evidence base is small and preliminary.

Generated Jun 10, 2026

Doses used in studies

g/day: 30–500 (median 222.5, IQR 67.5–420) — 2 studies

Time to effect

Median: 3 weeks · IQR 3 weeks–3 weeks · Range 3 weeks–3 weeks — Reported in 1 of 4 studies

4 of 4 papersPopulation:

Effects of replacing solid fats and added sugars with avocado in adults with elevated cardiometabolic risk: a randomized, double-blind, controlled feeding, crossover trial.
- 2026-02
- RCT
- The American journal of clinical nutrition 123(2)
- - Nana Gletsu-Miller
  - Meredith L Wilcox
  - Lisa A Spence
  - Amy J Wright
  - Liana L Guarneiri
  - Muhammad M Nadeem
  - Mark J Hutter
  - Karen L Sprague
  - Andrew W Brown
  - Allon N Friedman
  - Carol F Kirkpatrick
  - Kevin C Maki
- PubMed: 41397527
- DOI: 10.1016/j.ajcnut.2025.101137
12 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
An intention-to-treat analysis showed significantly larger percentage changes, 95% confidence intervals (CIs), from baseline after the avocado condition, compared with after the control condition, for ... TG (-17.4%; 95% CI: -25.0%, -8.99%; P < 0.001)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
1 avocado (∼180 g/d, ∼300 kcal/d)
Exploring the effect of avocado on lipid profile modulation: a systematic review and dose-response and meta-analysis of clinical trials.
- 2025-08
- Meta-Analysis
- Critical reviews in food science and nutrition 66(4)
- - Pariya Mostafazadeh
  - Sajjad Etesamnia
  - Mahdiyar Nasiraei-Moghadam
  - Alireza Jahan-Mihan
  - Alireza Haghighi
  - Abolfazl Zendedel
  - Soraiya Ebrahimpour-Koujan
- PubMed: 40749705
- DOI: 10.1080/10408398.2025.2531222
4 Insights on
- Reduced Triglyceride Levels
- High evidence
- Adults
Avocado consumption had no significant effect on high-density lipoprotein Cholesterol (HDL-C triglyceride (TG) levels.
Effect
Neutral
Effect size
Small
Significant
No
Is avocado beneficial for lipid profiles? An umbrella review of systematic reviews and meta-analyses.
- 2025-10
- Systematic Review
- Clinical nutrition ESPEN 69
- - Bruno M Candeloro
  - Sandra M Barbalho
  - Lucas Fornari Laurindo
  - Rodrigo D Raimundo
  - Beatriz L Stevanato
  - Maria C B Assumpção
  - Estela M D Casangel
  - Edson H Ito
  - Matheus C Barros
  - Andrey A Porto
  - David M Garner
  - Vitor E Valenti
- PubMed: 40876535
- DOI: 10.1016/j.clnesp.2025.08.019
9 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
Effects on ... TG (30-500 g/day) were inconsistent
Effect
Neutral
Effect size
Small
Significant
No
Dose
30-500 g/day
Effects of Avocado Products on Cardiovascular Risk Factors in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis.
- 2025-07-02
- Review
- Food science & nutrition 13(7)
- - Sahel Hamednia
  - Zahra Shouhani
  - Sara Tavakol
  - Nazanin Montazeri
  - Mohammadreza Amirkhan-Dehkordi
  - Mohammad Amin Karimi
  - Mehraveh Bastamkhani
  - Haleh Chavoshian Tabrizy
  - Ramin Amirsasan
  - Javad Vakili
  - Mehdi Karimi
  - Omid Asbaghi
- PubMed: 40612140
- DOI: 10.1002/fsn3.70547
9 Insights on
- Reduced Triglyceride Levels
- Low evidence
- Adults
avocado intake had no significant change on triglycerides (TG) (WMD: 0.02 mg/dL; p=0.97)
Effect
Neutral
Effect size
Small
Significant
No

avocado and Reduced Triglyceride Levels

Effects of replacing solid fats and added sugars with avocado in adults with elevated cardiometabolic risk: a randomized, double-blind, controlled feeding, crossover trial.

Exploring the effect of avocado on lipid profile modulation: a systematic review and dose-response and meta-analysis of clinical trials.

Is avocado beneficial for lipid profiles? An umbrella review of systematic reviews and meta-analyses.

Effects of Avocado Products on Cardiovascular Risk Factors in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis.