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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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brown rice and Reduced LDL Cholesterol

Research synthesisLow evidenceSmall effect3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, 1 reported a small beneficial effect on LDL cholesterol reduction, while 2 found neutral effects. The evidence base is limited and mixed, with benefits possibly limited to overweight individuals (BMI ≥ 25 kg/m²). The median study duration was 73 days, indicating effects were typically assessed after about 10 weeks.

  • Studied populations: overweight adults (BMI ≥ 25 kg/m²) with prediabetes, type 2 diabetes, or at risk for diabetes

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. The only significant beneficial effect was observed in a subgroup analysis of overweight individuals, highlighting potential heterogeneity in response.

Generated Jul 10, 2026
Time to effect
Median: 10.4 weeks · IQR 9.2 weeks–11.6 weeks · Range 8 weeks–3 months — Reported in 2 of 3 studies
3 of 3 papers
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