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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Cinnamon and Reduced Low-Density Lipoprotein Level

Research synthesisModerate evidenceMixed effect size3 studies · 3 beneficial · 0 neutral · 0 harmful

Across all 3 studies, cinnamon supplementation showed statistically significant beneficial effects on reducing LDL levels, with effect sizes ranging from small to large (two small, one large). The median study duration was 84 days, indicating effects typically observed at 12 weeks. The most studied populations include patients with type 2 diabetes, dyslipidemia, and PCOS; only one study specified a dose of 600 mg/day.

  • Studied populations: clinical populations with type 2 diabetes, dyslipidemia, and polycystic ovary syndrome (PCOS)

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, one study combined cinnamon with berberine, potentially confounding the specific effect of cinnamon, and the study reporting a large effect size had a small sample (n=30).

Generated Jul 5, 2026
Doses used in studies
  • mg/day: 600 (median 600, IQR 600–600) — 1 study
Time to effect
Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 3 studies
Safety in these studies
3 of 3 papers
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