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Evidence-Based Supplement Research
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Fenugreek Seed and Reduced Diastolic Blood Pressure

Research synthesisLow evidenceSmall effect3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, 1 reported a beneficial small effect of fenugreek seed supplementation on diastolic blood pressure, while 2 found neutral effects. The only statistically significant finding (p < 0.001) came from a small RCT in Alzheimer's patients using 5 cc of fenugreek seed extract over 120 days, while a meta-analysis and another RCT found no significant reduction. Evidence is limited and mixed, with no clear convergence on dose or population, and the median study duration was 88 days across two studies.

  • Studied populations: Alzheimer's disease patients with mild-to-moderate memory deficit

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. The sole beneficial finding was in a clinical population (Alzheimer's disease) and used a liquid extract form (5 cc), which may differ from typical powdered supplements.

Generated Jun 13, 2026
Doses used in studies
  • g/day: 15 (median 15, IQR 15–15) — 2 studies
  • cc/day: 5 (median 5, IQR 5–5) — 1 study
Time to effect
Median: 2.9 months · IQR 10.3 weeks–3.5 months · Range 8 weeks–4 months — Reported in 2 of 3 studies
3 of 3 papers
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