Brown and golden flaxseed reduce intestinal permeability and endotoxemia, and improve the lipid profile in perimenopausal overweight women.
- 2022-03-20
- RCT
- International journal of food sciences and nutrition 73(6)
- Cíntia Tomaz Sant'Ana
- Ariane Dias de Amorim
- Ana Paula Gava
- Carla Mora Aguilar
- Nayana Garcia Silva
- Líllian Duarte Machado
- Mirelle Lomar Viana
- Daniela da Silva Oliveira
- Pollyanna Ibrahim Silva
- Neuza Maria Brunoro Costa
- André Gustavo Vasconcelos Costa
- PubMed: 35311432
- DOI: 10.1080/09637486.2022.2052820
- High evidence
- Clinical
There was significant reduction in intestinal permeability in flaxseed groups, with delta of lactulose/mannitol ratio smaller (p ≤ 0.05).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 40 g/day for 12 weeks