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Evidence-Based Supplement Research

Evidence-Based Supplement Research

flaxseed and Reduced Blood Pressure

Doses used in studies

g/day: 20–30 (median 25, IQR 22.5–27.5) — 2 studies

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 2 studies

Safety in these studies

Overall tolerabilityNo significant difference
Changes in headache frequency or duration, as well as other measurements, were not significant between groups.
from: Effect of Flaxseed Supplementation on Headache Characteristics and Quality of Life in Pati

2 of 2 papersPopulation:

Effect of Flaxseed Supplementation on Headache Characteristics and Quality of Life in Patients with Migraine: A Randomized Controlled Trial.
- 2026-03
- RCT · n = 68
- The Journal of nutrition 156(3)
- - Amirhosein Jafarpour
  - Vahid Reza Ostovan
  - Masoumeh Akhlaghi
- PubMed: 41478596
- DOI: 10.1016/j.tjnut.2025.101312
10 Insights on
- Reduced Blood Pressure
- High evidence
- Clinical
Changes in headache frequency or duration, as well as other measurements, were not significant between groups.
Effect
Neutral
Effect size
Small
Significant
No
Dose
20 g/d
Dietary flaxseed: Cardiometabolic benefits and its role in promoting healthy aging.
- 2025-01-16
- Review
- GeroScience 47(3)
- - Setor K Kunutsor
  - Davinder S Jassal
  - Amir Ravandi
  - Andrea Lehoczki
- PubMed: 39821819
- DOI: 10.1007/s11357-025-01512-0
15 Insights on
- Reduced Blood Pressure
- Low evidence
Blood pressure reductions range from approximately 2 to 15 mmHg for systolic blood pressure and 1 to 7 mmHg for diastolic blood pressure
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
≥ 30 g/day for at least 12 weeks