flaxseed and Reduced Interleukin-6 Levels

• Effects of flaxseed supplementation on inflammatory biomarkers: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials.

  • 2024-10
  • Meta-Analysis · n = 3,000
  • Prostaglandins & other lipid mediators 174
  • • Vali Musazadeh
    • Reza Morovatshoar
    • Zeynab Kavyani
    • Mahdi Vajdi
    • Gholamreza Askari

  • PubMed: 38971216
  • DOI: 10.1016/j.prostaglandins.2024.106868

  3 Insights on

  • Reduced Interleukin-6 Levels

  • High evidence
  • Mixed

  and interleukin 6 (IL-6) (SMD = -0.64, 95 % CI: -1.13, -0.16, P = 0.010; I² = 92.7, P < 0.001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Dietary flaxseed: Cardiometabolic benefits and its role in promoting healthy aging.

  • 2025-01-16
  • Review
  • GeroScience 47(3)
  • • Setor K Kunutsor
    • Davinder S Jassal
    • Amir Ravandi
    • Andrea Lehoczki

  • PubMed: 39821819
  • DOI: 10.1007/s11357-025-01512-0

  15 Insights on

  • Reduced Interleukin-6 Levels

  • Low evidence

  Flaxseed supplementation significantly improves several cardiometabolic risk factors, including markers of inflammation (e.g., C-reactive protein and interleukin-6)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  ≥ 30 g/day for at least 12 weeks