Goldenseal Root and Reduced Depression Symptoms

• Marked Improvement in Treatment-Intolerant Obsessive-Compulsive Disorder in an Adolescent Using a Glutamatergic Regimen With Dextromethorphan, Piracetam, and Goldenseal Root.

  • 2026-03-03
  • Case Report
  • Cureus 18(3)
  • • Ngo Cheung

  • PubMed: 41783550
  • DOI: 10.7759/cureus.104617

  2 Insights on

  • Reduced Depression Symptoms

  • Low evidence

  PHQ-9 score fell to 2

  Effect

  Beneficial

  Effect size

  Large

  Dose

  600 mg/day