Effect of an aqueous extract of Terminalia chebula on endothelial dysfunction, systemic inflammation, and lipid profile in type 2 diabetes mellitus: A randomized double-blind, placebo-controlled clinical study.
- 2020-07-02
- RCT · n = 60
- Phytotherapy research : PTR 34(12)
- Usharani Pingali
- Deepasree Sukumaran
- Chandrasekhar Nutalapati
- PubMed: 32618037
- DOI: 10.1002/ptr.6771
- High evidence
- Clinical
Treatment with T. chebula 250 mg and T. chebula 500 mg for 12 weeks significantly improved the endothelial function (reflection index) compared to placebo (absolute changes: - T. chebula 250: -2.55 ± 1.82% vs. T. chebula 500: -5.21 ± 2.41% vs. placebo: 1.40 ± 2.11%).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 500 mg twice daily