Best Supplements for Improved Vascular Endothelial Function
Ranked by research evidence. Compare 15 supplements across 17 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence3 studies
Across 3 studies, all reported beneficial effects on vascular endothelial function, with effect sizes ranging from small to moderate (predominantly small). One mouse study showed statistically significant improvements, while two human RCTs (likely from the same trial) found trending but non-significant improvements (p=0.05). The evidence is limited to a single human trial and one animal study; no consistent dose, form, or duration data were available. Populations studied include healthy adults aged 18–65 with BMI 20–34.9 and Western-diet-fed mice.
15 supplements
- LowBacillus subtilis DE111Across 3 studies, all reported beneficial effects on vascular endothelial function, with effect sizes ranging from small to moderate (predominantly small). One mouse study showed statistically significant improvements, while two human RCTs (likely from the same trial) found trending but non-significant improvements (p=0.05). The evidence is limited to a single human trial and one animal study; no consistent dose, form, or duration data were available. Populations studied include healthy adults aged 18–65 with BMI 20–34.9 and Western-diet-fed mice.1 beneficial2 neutral3 studies