Propolis and Reduced HOMA-IR

• Propolis effects on blood sugar and lipid metabolism, inflammatory indicators, and oxidative stress in people with type 2 diabetes: a systematic review and meta-analysis.

  • 2025-10-09
  • Systematic Review · n = 731
  • Frontiers in nutrition 12
  • • Yihua Zhang
    • Shuo Ding
    • Wenjing Li
    • Xiumei Wang
    • Jie Lv
    • Qingmei Niu
    • Qian Zhang

  • PubMed: 41141253
  • DOI: 10.3389/fnut.2025.1653730

  12 Insights on

  • Reduced HOMA-IR

  • High evidence
  • Clinical

  homeostasis model assessment of insulin resistance (HOMA-IR) (MD = -0.95, 95% CI: -1.36 to -0.55, p < 0.00001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Propolis supplementation improves cardiometabolic health in patients with type 2 diabetes mellitus: findings from a GRADE-assessed systematic review and meta-analysis of RCTs.

  • 2025-07-12
  • Review
  • Journal of diabetes and metabolic disorders 24(2)
  • • Mehdi Karimi
    • Nazgol Bahreini
    • Samira Pirzad
    • Seyed Morteza Ali Pourfaraji
    • Niyusha Shirsalimi
    • Omid Asbaghi
    • Bagher Larijani

  • PubMed: 40662144
  • DOI: 10.1007/s40200-025-01682-w

  13 Insights on

  • Reduced HOMA-IR

  • Low evidence
  • Clinical

  Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) (WMD: -0.99)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes