Propolis and Reduced Triglyceride Levels

Research synthesisModerate evidenceSmall effect3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 studies (all systematic reviews or meta-analyses), 2 reported beneficial small-sized effects of propolis supplementation on reducing triglyceride levels, while 1 found no significant change. The beneficial effects were observed primarily in populations with type 2 diabetes and adults at risk of metabolic syndrome. Study durations and doses were not consistently reported across the evidence base.

Studied populations: people with type 2 diabetes, adults at risk of metabolic syndrome

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Doses and forms were not consistently reported across studies, limiting dosage recommendations. One neutral study showed a non-significant trend (p=0.055), suggesting possible effect but not definitive.

Generated Jul 18, 2026

3 of 3 papers

Propolis effects on blood sugar and lipid metabolism, inflammatory indicators, and oxidative stress in people with type 2 diabetes: a systematic review and meta-analysis.
- 2025-10-09
- Systematic Review · n = 731
- Frontiers in nutrition 12
- - Yihua Zhang
  - Shuo Ding
  - Wenjing Li
  - Xiumei Wang
  - Jie Lv
  - Qingmei Niu
  - Qian Zhang
- PubMed: 41141253
- DOI: 10.3389/fnut.2025.1653730
12 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
reduced triglyceride (TG) levels (MD = -0.15, 95% CI: -0.30 to -0.01; p = 0.04)
Effect
Beneficial
Effect size
Small
Significant
Yes
Propolis Supplementation and Metabolic Syndrome Components in Adults at Risk: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
- 2026-02-25
- Review · n = 1,091
- Health science reports 9(3)
- - Safia Obaidur Rab
  - Mudher Kadhem
  - Malathi H
  - Swati Mishra
  - Ishant Arora
  - Mehran Nouri
- PubMed: 41767366
- DOI: 10.1002/hsr2.71909
6 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
The results indicated that propolis supplementation significantly reduced ... triglyceride (TG) levels (WMD: -12.32 mg/dL, 95% CI: -21.08 to -3.56, p = 0.006)
Effect
Beneficial
Effect size
Small
Significant
Yes
Propolis supplementation improves cardiometabolic health in patients with type 2 diabetes mellitus: findings from a GRADE-assessed systematic review and meta-analysis of RCTs.
- 2025-07-12
- Review
- Journal of diabetes and metabolic disorders 24(2)
- - Mehdi Karimi
  - Nazgol Bahreini
  - Samira Pirzad
  - Seyed Morteza Ali Pourfaraji
  - Niyusha Shirsalimi
  - Omid Asbaghi
  - Bagher Larijani
- PubMed: 40662144
- DOI: 10.1007/s40200-025-01682-w
13 Insights on
- Reduced Triglyceride Levels
- Low evidence
- Clinical
no significant changes in triglycerides (TG) (p = 0.055)
Effect
Neutral
Effect size
Small
Significant
No

Propolis and Reduced Triglyceride Levels

Propolis effects on blood sugar and lipid metabolism, inflammatory indicators, and oxidative stress in people with type 2 diabetes: a systematic review and meta-analysis.

Propolis Supplementation and Metabolic Syndrome Components in Adults at Risk: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Propolis supplementation improves cardiometabolic health in patients with type 2 diabetes mellitus: findings from a GRADE-assessed systematic review and meta-analysis of RCTs.