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Evidence-Based Supplement Research

Evidence-Based Supplement Research

prune and Increased Total Serum Antioxidant Capacity

Doses used in studies

g/day: 50–100 (median 75, IQR 50–100) — 1 study
kcal/day: 200 (median 200, IQR 200–200) — 1 study

Time to effect

Median: 7 months · IQR 4.4 months–9.6 months · Range 8 weeks–12.2 months — Reported in 2 of 2 studies

2 of 2 papersPopulation:

Prune Consumption Attenuates Proinflammatory Cytokine Secretion and Alters Monocyte Activation in Postmenopausal Women: Secondary Outcome Analysis of a 12-Mo Randomized Controlled Trial: The Prune Study.
- 2024-05
- RCT · n = 235
- The Journal of nutrition 154(5)
- - Janhavi J Damani
  - Ester S Oh
  - Mary Jane De Souza
  - Nicole Ca Strock
  - Nancy I Williams
  - Cindy H Nakatsu
  - Hang Lee
  - Connie Weaver
  - Connie J Rogers
- PubMed: 37984741
- DOI: 10.1016/j.tjnut.2023.11.014
10 Insights on
- Increased Total Serum Antioxidant Capacity
- High evidence
- Large Human Trial
- Elderly
Prune supplementation did not alter hs-CRP, TAC, 8-isoprostane, and plasma cytokine concentrations.
Effect
Neutral
Effect size
Small
Significant
No
Dose
50 g prune/d and 100 g prune/d
Snack selection influences glucose metabolism, antioxidant capacity and cholesterol in healthy overweight adults: A randomized parallel arm trial.
- 2019-05
- RCT
- Nutrition research (New York, N.Y.) 65
- - Zachary S Clayton
  - Elizabeth Fusco
  - Lisa Schreiber
  - Jennifer N Carpenter
  - Shirin Hooshmand
  - Mee Young Hong
  - Mark Kern
- PubMed: 30952505
- DOI: 10.1016/j.nutres.2019.03.002
21 Insights on
- Increased Total Serum Antioxidant Capacity
- High evidence
- Adults
DP increased (P<.05) overall intake of dietary fiber and potassium, and TAC
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
100 kcal servings twice-daily