Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

red yeast rice and Reduced Apolipoprotein B Levels

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects of red yeast rice on reducing apolipoprotein B levels, with effect sizes ranging from moderate to large. Two of the three studies reported statistically significant findings. The median study duration was 56 days (8 weeks), suggesting effects are observed within this timeframe. The most-studied population appears to be individuals with hyperlipidemia or mild dyslipidemia, with doses varying from 200 mg/day to 4800 mg/day (or up to 10 mg/day monacolin K). The evidence shows moderate-sized effects on apoB reduction.

  • Effective dose range: 200-4800 mg/day (or up to 10 mg/day monacolin K)
  • Studied populations: individuals with hyperlipidemia or mild dyslipidemia

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Two of the three studies are reviews/meta-analyses, and the only primary RCT had a very small sample size (18 patients).

Generated Jun 10, 2026
Doses used in studies
  • mg/day: 10–4,800 (median 200, IQR 105–2,500) — 3 studies
Time to effect
Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 3 studies
Safety in these studies
3 of 3 papers
Back to top