Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

red yeast rice and Reduced Blood Pressure

Doses used in studies

mg/day: 10–200 (median 105, IQR 57.5–152.5) — 2 studies

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 2 studies

Safety in these studies

Overall tolerabilityReported
No severe treatment-related adverse effects on muscles, liver, or renal function were observed.
from: Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japa

2 of 2 papersPopulation:

Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial.
- 2021-09-01
- RCT
- Asia Pacific journal of clinical nutrition 30(3)
- - Takuya Minamizuka
  - Masaya Koshizaka
  - Mayumi Shoji
  - Masaya Yamaga
  - Aiko Hayashi
  - Kana Ide
  - Shintaro Ide
  - Takumi Kitamoto
  - Kenichi Sakamoto
  - Akiko Hattori
  - Takahiro Ishikawa
  - Junji Kobayashi
  - Yoshiro Maezawa
  - Kazuki Kobayashi
  - Minoru Takemoto
  - Masaru Inagaki
  - Akira Endo
  - Koutaro Yokote
- PubMed: 34587702
- DOI: 10.6133/apjcn.202109_30(3).0009
4 Insights on
- Reduced Blood Pressure
- High evidence
- Clinical
The red yeast rice group also exhibited significant decreases in total cholesterol, apolipoprotein B, and blood pressure.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
200 mg/day
Red yeast rice with monacolin K for the improvement of hyperlipidemia: A narrative review.
- 2025-09-26
- Review
- World journal of clinical cases 13(27)
- - Kevan English
- PubMed: 40881894
- DOI: 10.12998/wjcc.v13.i27.105415
3 Insights on
- Reduced Blood Pressure
- Low evidence
lower levels of ... blood pressure
Effect
Beneficial
Effect size
Moderate
Dose
up to 10 mg/day (monacolin K)